OTOBIOTIC EAR DROPS 10ML

INGREDIENTS

CIPROFLOXACIN is a fluoroquinolone that has a broad spectrum of activity against otic
pathogens but lacks the capacity for ototoxicity. Hence ciprofloxacin is preferred to amino
glycosides for any application within the middle ear space. It exerts its antibacterial activity by
inhibiting DNA gyrase, a bacterial enzyme that is essential in DNA replication, repair,
deactivation and transcription.
BECLOMETHASONE has anti-inflammatory, antipruritic and vasoconstrictive properties.
CLOTRIMAZOLE is a synthetic imidazole derivative; it is a broad-spectrum antifungal agent
responsible for superficial mycotic infections affecting the outer or middle ear including Candida,
Microsporum and Trichophyton.
CLOTRIMAZOLE also has activity against certain grams-positive bacteria such as streptococci
and staphylococci
LIGNOCAINE HCL is a topical anesthetic with a low index of sensitization and toxicity so helps
reduce pain and stinging in the ear.

INDICATIONS:
OTOBIOTIC EAR DROPS by virtue of its three active ingredients has antibacterial, antifungal
and anti- inflammatory activity of the ear. It is recommended for the treatment of superficial
bacterial and fungal infections of the external auditory canal caused by organisms susceptible to
the action of ciprofloxacin and clotrimazole.

DOSAGEANDADMINISTRATION
Adults and children
Apply 3-5 drops of OTOBIOTIC Ear Drops into the affected ear.
To apply tilt head to one side so that the ear is facing up.
Then gently pull the ear lobe backward and upward in case of adults and children older than 3
years
For children younger than 3 years gently pull the ear lobe backward and down apply 3-5 drops
of otobiotic into the ear.
Keep head tilted for about 5 minutes to allow the drops to penetrate lower into the ear canal.
Gently pat excess material dripping out of the ear using a clean cotton ball.
Follow these instructions 3-4 times a day for 7-14 days.
If the ear canal is swollen consider inserting a wick to allow topical treatment to travel along the
length of the ear canal .The wick should be saturated with the ear drops. The wick should be
moistened for the first 24 hours by occasionally adding a few drops on the wick. Remove the
wick after the first 24 hours and continue to instill 5 drops for adults and 3 drops for children,
otobiotic3 or 4 times daily thereafter.

CONTRAINDICATIONS
Patients sensitive to ciprofloxacin or other quinolones